Need latest navigation dvd for es 350 2009 model gcc. 

Nope sorry nothing

Ahaaan, And any advice where to buy a lexus IS300 or 250 from. Any specific things i should look for before i buy the car with american specs?

I wouldn't touch an American import with a 10 ft pole unless I saw it being unloaded from the container it came in and then repaired it to my satisfaction at a place I trust There is a reason why these cars where there is a big demand for good cheap 2nd hand cars end up here. Some have minor damage like a small to medium sized fender bender to being flood damaged and rusted to shit. 

well they are good congested sportys but keep your eyes open for any vsc or abs lights as it will easily set you back from 8 to 12k to fix it...

GCC got IS300 while US spec is IS350. That is why you dont yet it easily.