As said, signs of wear and tear generally point to high miles. Worn pedal rubbers, gearstick, steering wheel, drivers seat bolster.
On a car with old style analogue odometer, make sure the numbers are all in a straight line, if one or more are slightly out of line, there is a chance it has been tampered with. Also check the screws on the dashboard above the steering wheel for marks caused by screwdrivers/torx or other tools. Also a good sign that someone has been in there tampering.
On cars with digital odometer it's a bit more difficult to tell for sure without plugging it into a computer. Some cars log the correct mileage in the ECU whilst the display can show something completely different but the ECU will always have the correct miles. It's so easy to change the mileage on digital odometers too, all you need is a laptop, a lead and a piece of torrented software and you can change the mileage on many cars in a few minutes.
On a side note, I once worked on a car in the UK and had to remove the dash clocks to fit a bulb and found a note stuck to the back saying 'Third time clocked LOL'. Some people have no shame.